VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities

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The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without virB, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional silencing mediated by the nucleoid structuring protein, H-N...

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Detalles Bibliográficos
Autores principales: Gerson, Taylor M., Ott, Audrey M., Karney, Monika M. A., Socea, Jillian N., Ginete, Daren R., Iyer, Lakshminarayan M., Aravind, L., Gary, Ronald K., Wing, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653881/
https://www.ncbi.nlm.nih.gov/pubmed/37728345
http://dx.doi.org/10.1128/mbio.01519-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653881/
https://www.ncbi.nlm.nih.gov/pubmed/37728345
http://dx.doi.org/10.1128/mbio.01519-23

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