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VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without virB, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional silencing mediated by the nucleoid structuring protein, H-N...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653881/ https://www.ncbi.nlm.nih.gov/pubmed/37728345 http://dx.doi.org/10.1128/mbio.01519-23 |
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por Gerson, Taylor M., Ott, Audrey M., Karney, Monika MA., Socea, Jillian N., Ginete, Daren R., Iyer, Lakshminarayan M., Aravind, L., Gary, Ronald K., Wing, Helen J.
Publicado 2023
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Publicado 2023
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Online
Artículo
Texto