Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons

Tuberculosis (TB) is one of the leading causes of death due to an infectious disease. The rise of multi-drug resistance (MDR) in Mycobacterium tuberculosis (Mtb), the causative agent of TB, presents a significant obstacle to TB control. While human studies report dysregulated immune responses during...

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Detalles Bibliográficos
Autores principales: Bobba, Suhas, Howard, Nicole C., Das, Shibali, Ahmed, Mushtaq, Tang, Linrui, Thirunavukkarasu, Shyamala, Larsen, Michelle H., Mathema, Barun, Divangahi, Maziar, Khader, Shabaana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653897/
https://www.ncbi.nlm.nih.gov/pubmed/37682004
http://dx.doi.org/10.1128/mbio.00946-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653897/
https://www.ncbi.nlm.nih.gov/pubmed/37682004
http://dx.doi.org/10.1128/mbio.00946-23

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