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Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons
Tuberculosis (TB) is one of the leading causes of death due to an infectious disease. The rise of multi-drug resistance (MDR) in Mycobacterium tuberculosis (Mtb), the causative agent of TB, presents a significant obstacle to TB control. While human studies report dysregulated immune responses during...
Autores principales: | Bobba, Suhas, Howard, Nicole C., Das, Shibali, Ahmed, Mushtaq, Tang, Linrui, Thirunavukkarasu, Shyamala, Larsen, Michelle H., Mathema, Barun, Divangahi, Maziar, Khader, Shabaana A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653897/ https://www.ncbi.nlm.nih.gov/pubmed/37682004 http://dx.doi.org/10.1128/mbio.00946-23 |
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