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Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response

The Epstein-Barr virus (EBV) efficiently transforms primary B cells. Here, we show that this process starts immediately after cellular exposure to infectious viral particles. Virus binding to B cells led to the activation of intracytoplasmic tyrosine kinases and STAT3. Tegument proteins within the v...

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Detalles Bibliográficos
Autores principales: Baccianti, Francesco, Masson, Charlène, Delecluse, Susanne, Li, Zhe, Poirey, Remy, Delecluse, Henri-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653912/
https://www.ncbi.nlm.nih.gov/pubmed/37830871
http://dx.doi.org/10.1128/mbio.01784-23

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