Deep mutational scanning of influenza A virus neuraminidase facilitates the identification of drug resistance mutations in vivo

Neuraminidase (NA) is a pivotal surface enzyme and a key therapeutic target in combating the influenza A virus. Its evolution can lead to potential zoonotic transmission, seasonal epidemics, and the emergence of drug-resistant mutants. To gain comprehensive insights into the mutational effects and d...

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Detalles Bibliográficos
Autores principales: Wang, Sihan, Zhang, Tian-hao, Hu, Menglong, Tang, Kejun, Sheng, Li, Hong, Mengying, Chen, Dongdong, Chen, Liubo, Shi, Yuan, Feng, Jun, Qian, Jing, Sun, Lifeng, Ding, Kefeng, Sun, Ren, Du, Yushen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654105/
https://www.ncbi.nlm.nih.gov/pubmed/37772870
http://dx.doi.org/10.1128/msystems.00670-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654105/
https://www.ncbi.nlm.nih.gov/pubmed/37772870
http://dx.doi.org/10.1128/msystems.00670-23

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