Cargando…
Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock
OBJECTIVES: To investigate the changes in the coagulation function and hemodynamic parameters in patients with Hemorrhagic Traumatic Shock (HTS) after restrictive fluid resuscitation. METHODS: A total of 139 patients with HTS admitted to our hospital were enrolled, among which 69 HTS patients were d...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654136/ https://www.ncbi.nlm.nih.gov/pubmed/37931530 http://dx.doi.org/10.1016/j.clinsp.2023.100300 |
_version_ | 1785136563020103680 |
---|---|
author | Zheng, Junfen Zhu, Jinqiang Cao, Liexiang Dong, Meiping Mao, Yi Zhao, Zhiwei Liu, Yao |
author_facet | Zheng, Junfen Zhu, Jinqiang Cao, Liexiang Dong, Meiping Mao, Yi Zhao, Zhiwei Liu, Yao |
author_sort | Zheng, Junfen |
collection | PubMed |
description | OBJECTIVES: To investigate the changes in the coagulation function and hemodynamic parameters in patients with Hemorrhagic Traumatic Shock (HTS) after restrictive fluid resuscitation. METHODS: A total of 139 patients with HTS admitted to our hospital were enrolled, among which 69 HTS patients were divided into the control group and the remaining 70 HTS patients as the observation group. Patients in the control group underwent regular fluid resuscitation, while those in the observation group underwent restrictive fluid resuscitation. RESULTS: During treatment, 70 patients in the observation group had a lower bleeding amount, infusion amount, and blood transfusion volume than those in the control group (p < 0.05). After treatment, patients in the observation group had better hemodynamic parameters and blood coagulation than those in the control group (p < 0.05), and the incidence rate in the observation group was only 12.9%, which was significantly lower than 60.87% in the control group, while the cure rate in the observation group was 100%, which was significantly higher than that in the control group (p < 0.05). CONCLUSIONS: Restrictive fluid resuscitation could remarkably increase the cure rate and reduce the bleeding amount during HTS treatment, thereby benefiting the recovery of the patient's blood coagulation. |
format | Online Article Text |
id | pubmed-10654136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-106541362023-11-04 Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock Zheng, Junfen Zhu, Jinqiang Cao, Liexiang Dong, Meiping Mao, Yi Zhao, Zhiwei Liu, Yao Clinics (Sao Paulo) Original Articles OBJECTIVES: To investigate the changes in the coagulation function and hemodynamic parameters in patients with Hemorrhagic Traumatic Shock (HTS) after restrictive fluid resuscitation. METHODS: A total of 139 patients with HTS admitted to our hospital were enrolled, among which 69 HTS patients were divided into the control group and the remaining 70 HTS patients as the observation group. Patients in the control group underwent regular fluid resuscitation, while those in the observation group underwent restrictive fluid resuscitation. RESULTS: During treatment, 70 patients in the observation group had a lower bleeding amount, infusion amount, and blood transfusion volume than those in the control group (p < 0.05). After treatment, patients in the observation group had better hemodynamic parameters and blood coagulation than those in the control group (p < 0.05), and the incidence rate in the observation group was only 12.9%, which was significantly lower than 60.87% in the control group, while the cure rate in the observation group was 100%, which was significantly higher than that in the control group (p < 0.05). CONCLUSIONS: Restrictive fluid resuscitation could remarkably increase the cure rate and reduce the bleeding amount during HTS treatment, thereby benefiting the recovery of the patient's blood coagulation. Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2023-11-04 /pmc/articles/PMC10654136/ /pubmed/37931530 http://dx.doi.org/10.1016/j.clinsp.2023.100300 Text en © 2023 HCFMUSP. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Articles Zheng, Junfen Zhu, Jinqiang Cao, Liexiang Dong, Meiping Mao, Yi Zhao, Zhiwei Liu, Yao Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title | Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title_full | Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title_fullStr | Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title_full_unstemmed | Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title_short | Effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
title_sort | effect of restrictive fluid resuscitation on the coagulation function and hemodynamic parameters in patients with hemorrhagic traumatic shock |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654136/ https://www.ncbi.nlm.nih.gov/pubmed/37931530 http://dx.doi.org/10.1016/j.clinsp.2023.100300 |
work_keys_str_mv | AT zhengjunfen effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT zhujinqiang effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT caoliexiang effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT dongmeiping effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT maoyi effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT zhaozhiwei effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock AT liuyao effectofrestrictivefluidresuscitationonthecoagulationfunctionandhemodynamicparametersinpatientswithhemorrhagictraumaticshock |