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New ex vivo method to objectively assess insulin spatial subcutaneous dispersion through time during pump basal-rate based administration

Glycemic variability remains frequent in patients with type 1 diabetes treated with insulin pumps. Heterogeneous spreads of insulin infused by pump in the subcutaneous (SC) tissue are suspected but were barely studied. We propose a new real-time ex-vivo method built by combining high-precision imagi...

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Detalles Bibliográficos
Autores principales: Jacquemier, Pauline, Retory, Yann, Virbel-Fleischman, Clara, Schmidt, Alexandra, Ostertag, Agnes, Cohen-Solal, Martine, Alzaid, Fawaz, Potier, Louis, Julla, Jean-Baptiste, Gautier, Jean-François, Venteclef, Nicolas, Riveline, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654403/
https://www.ncbi.nlm.nih.gov/pubmed/37973963
http://dx.doi.org/10.1038/s41598-023-46993-1