Cargando…
Impaired Autophagic Flux in Glucose-Deprived Cells: An Outcome of Lysosomal Acidification Failure Exacerbated by Mitophagy Dysfunction
Autophagy dysfunction is associated with human diseases and conditions including neurodegenerative diseases, metabolic issues, and chronic infections. Additionally, the decline in autophagic activity contributes to tissue and organ dysfunction and aging-related diseases. Several factors, such as dow...
Autores principales: | Hwang, Eun Seong, Song, Seon Beom |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654461/ https://www.ncbi.nlm.nih.gov/pubmed/37867391 http://dx.doi.org/10.14348/molcells.2023.0121 |
Ejemplares similares
-
High Levels of ROS Impair Lysosomal Acidity and Autophagy Flux in Glucose-Deprived Fibroblasts by Activating ATM and Erk Pathways
por: Song, Seon Beom, et al.
Publicado: (2020) -
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes
por: Kim, Hyeon‐Ji, et al.
Publicado: (2021) -
Development of Research into Autophagic Lysosome Reformation
por: Chen, Yang, et al.
Publicado: (2018) -
Ubiquilins Regulate Autophagic Flux through mTOR Signaling and Lysosomal Acidification
por: Şentürk, Mümine, et al.
Publicado: (2019) -
AB77. Tetrandrine blocks autophagic flux by preventing lysosomal acidification in 786-O cells
por: Gong, Yanqing, et al.
Publicado: (2014)