Aryl hydrocarbon receptor is a tumor promoter in MYCN-amplified neuroblastoma cells through suppression of differentiation

Neuroblastoma is the most common extracranial solid tumor in children. MYCN amplification is detected in almost half of high-risk cases and is associated with poorly differentiated tumors, poor patient prognosis and poor response to therapy, including retinoids. We identify the aryl hydrocarbon rece...

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Detalles Bibliográficos
Autores principales: Chaudhry, Kanita A., Jacobi, Justine J., Gillard, Bryan M., Karasik, Ellen, Martin, Jeffrey C., da Silva Fernandes, Tatiane, Hurley, Edward, Feltri, Maria Laura, Attwood, Kristopher M., Twist, Clare J., Smiraglia, Dominic J., Long, Mark D., Bianchi-Smiraglia, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654598/
https://www.ncbi.nlm.nih.gov/pubmed/38026169
http://dx.doi.org/10.1016/j.isci.2023.108303

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