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Modulating the dynamics of NFκB and PI3K enhances the ensemble-level TNFR1 signaling mediated apoptotic response

Cell-to-cell variability during TNFα stimulated Tumor Necrosis Factor Receptor 1 (TNFR1) signaling can lead to single-cell level pro-survival and apoptotic responses. This variability stems from the heterogeneity in signal flow through intracellular signaling entities that regulate the balance betwe...

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Detalles Bibliográficos
Autores principales:	Sherekar, Shubhank, Todankar, Chaitra S., Viswanathan, Ganesh A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654705/ https://www.ncbi.nlm.nih.gov/pubmed/37973854 http://dx.doi.org/10.1038/s41540-023-00318-0

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