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Joint multi-ancestry and admixed GWAS reveals the complex genetics behind human cranial vault shape

The cranial vault in humans is highly variable, clinically relevant, and heritable, yet its genetic architecture remains poorly understood. Here, we conduct a joint multi-ancestry and admixed multivariate genome-wide association study on 3D cranial vault shape extracted from magnetic resonance image...

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Detalles Bibliográficos
Autores principales: Goovaerts, Seppe, Hoskens, Hanne, Eller, Ryan J., Herrick, Noah, Musolf, Anthony M., Justice, Cristina M., Yuan, Meng, Naqvi, Sahin, Lee, Myoung Keun, Vandermeulen, Dirk, Szabo-Rogers, Heather L., Romitti, Paul A., Boyadjiev, Simeon A., Marazita, Mary L., Shaffer, John R., Shriver, Mark D., Wysocka, Joanna, Walsh, Susan, Weinberg, Seth M., Claes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654897/
https://www.ncbi.nlm.nih.gov/pubmed/37973980
http://dx.doi.org/10.1038/s41467-023-43237-8