SARS-CoV-2 N protein induced acute kidney injury in diabetic db/db mice is associated with a Mincle-dependent M1 macrophage activation

“Cytokine storm” is common in critically ill COVID-19 patients, however, mechanisms remain largely unknown. Here, we reported that overexpression of SARS-CoV-2 N protein in diabetic db/db mice significantly increased tubular death and the release of HMGB1, one of the damage-associated molecular patt...

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Detalles Bibliográficos
Autores principales: Wu, Wenjing, Wang, Wenbiao, Liang, Liying, Chen, Junzhe, Sun, Sifan, Wei, Biao, Zhong, Yu, Huang, Xiao-Ru, Liu, Jian, Wang, Xiaoqin, Yu, Xueqing, Lan, Hui-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655021/
https://www.ncbi.nlm.nih.gov/pubmed/38022581
http://dx.doi.org/10.3389/fimmu.2023.1264447

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