BMP2 gene transfer induces pericardial effusion and inflammatory response in the ischemic porcine myocardium

Pro-angiogenic gene therapy is being developed to treat coronary artery disease (CAD). We recently showed that bone morphogenetic protein 2 (BMP2) and vascular endothelial growth factor-A synergistically regulate endothelial cell sprouting in vitro. BMP2 was also shown to induce endocardial angiogen...

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Detalles Bibliográficos
Autores principales: Pulkkinen, H. H., Kivistö-Rahnasto, A., Korpela, H., Heikkilä, M., Järveläinen, N., Siimes, S., Kilpeläinen, L., Laham-Karam, N., Ylä-Herttuala, S., Laakkonen, J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655027/
https://www.ncbi.nlm.nih.gov/pubmed/38028463
http://dx.doi.org/10.3389/fcvm.2023.1279613

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