Cargando…

Clinical implications of PNA‑sequencing as a complementary test for EGFR mutation analysis in human lung cancer

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are the first-line regimen for the treatment of non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, false-negative results are occasionally observed, even with FDA-approved molecular tests. Such examples in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yi-Lin, Lin, Chien-Chung, Yu, Yu-Ting, Chen, Wan-Li, Yang, Shu-Ching, Huang, Wenya, Su, Wu-Chou, Chow, Nan-Haw, Ho, Chung-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655035/ https://www.ncbi.nlm.nih.gov/pubmed/38020305 http://dx.doi.org/10.3892/ol.2023.14126

Ejemplares similares

Epidermal Growth Factor Receptor Mutation and Anaplastic Lymphoma Kinase Gene Fusion: Detection in Malignant Pleural Effusion by RNA or PNA Analysis
por: Chen, Yi-Lin, et al.
Publicado: (2016)

Five Technologies for Detecting the EGFR T790M Mutation in the Circulating Cell-Free DNA of Patients With Non-small Cell Lung Cancer: A Comparison
por: Chen, Yi-Lin, et al.
Publicado: (2019)

High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma
por: Huang, Wenya, et al.
Publicado: (2023)

Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping
por: Kim, Hye-Ryoun, et al.
Publicado: (2013)

Development of a novel ALK rearrangement screening test for non–small cell lung cancers
por: Chen, Yi-Lin, et al.
Publicado: (2021)

Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology
por: Ackermann, Damian, et al.
Publicado: (2013)

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation
por: Guha, Minakshi, et al.
Publicado: (2013)

EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method
por: Watanabe, Kana, et al.
Publicado: (2016)

Association of EGFR Tyrosine Kinase Inhibitor Treatment With Progression-Free Survival Among Taiwanese Patients With Advanced Lung Adenocarcinoma and EGFR Mutation
por: Chen, Po-Yen, et al.
Publicado: (2021)

Chemotherapy outcomes in EGFR‐TKI resistant patients with common and uncommon EGFR mutation: An exploratory retrospective cohort study
por: Lin, Chien‐Yu, et al.
Publicado: (2023)

The Impact of Sequence of Chemotherapy and EGFR-TKI Treatment on Different EGFR Mutation Lung Adenocarcinoma
por: Chung, Fu-Tsai, et al.
Publicado: (2015)

Fluorogenic PNA probes
por: Vilaivan, Tirayut
Publicado: (2018)

Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide
por: Xu, Xiaojun, et al.
Publicado: (2019)

Preventing and treating brain metastases with three first-line EGFR-tyrosine kinase inhibitors in patients with EGFR mutation-positive advanced non-small cell lung cancer
por: Su, Po-Lan, et al.
Publicado: (2018)

Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase Inhibitor Treatment
por: Lee, Hyun Ju, et al.
Publicado: (2013)

The Emergent Landscape of Detecting EGFR Mutations Using Circulating Tumor DNA in Lung Cancer
por: Huang, Wei-Lun, et al.
Publicado: (2015)

The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches—toward anti-sense therapy against TREDs
por: Kiliszek, Agnieszka, et al.
Publicado: (2016)

First‐line treatment with irreversible tyrosine kinase inhibitors associated with longer OS in EGFR mutation‐positive non‐small cell lung cancer
por: Su, Po‐Lan, et al.
Publicado: (2020)

Synthesis of PNA Oligoether Conjugates
por: Ghidini, Alice, et al.
Publicado: (2014)

Selective recognition of DNA from olive leaves and olive oil by PNA and modified-PNA microarrays
por: Rossi, Stefano, et al.
Publicado: (2012)

Improved survival in patients with unresectable stage III EGFR ‐mutant adenocarcinoma with upfront EGFR‐tyrosine kinase inhibitors
por: Wang, Sheng‐Yuan, et al.
Publicado: (2021)

Brain MRI imaging characteristics predict treatment response and outcome in patients with de novo brain metastasis of EGFR-mutated NSCLC
por: Lin, Chia-Ying, et al.
Publicado: (2019)

Economic Analysis of Tissue-First, Plasma-First, and Complementary NGS Approaches for Treatment-Naïve Metastatic Lung Adenocarcinoma
por: Yang, Szu-Chun, et al.
Publicado: (2022)

In vivo correction of cystic fibrosis mediated by PNA nanoparticles
por: Piotrowski-Daspit, Alexandra S., et al.
Publicado: (2022)

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis
por: Kim, Chang Gon, et al.
Publicado: (2017)

HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells
por: Chou, Chia-Wei, et al.
Publicado: (2011)

The impact of EGFR mutations on the incidence and survival of stages I to III NSCLC patients with subsequent brain metastasis
por: Chang, Wei-Yuan, et al.
Publicado: (2018)

γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity
por: Avitabile, Concetta, et al.
Publicado: (2012)

Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry
por: Wiessler, Manfred, et al.
Publicado: (2010)

Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting
por: Myrhammar, Anders, et al.
Publicado: (2020)

Comparative Evaluation of Novel (177)Lu-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting
por: Tano, Hanna, et al.
Publicado: (2021)

Parameterization of the miniPEG-Modified γPNA Backbone: Toward Induced γPNA Duplex Dissociation
por: Tamez, Angel, et al.
Publicado: (2023)

EGFR Tyrosine Kinase Inhibitor Efficacy in Older Adult Patients with Advanced EGFR-Mutated Non-Small-Cell Lung Cancer: A Meta-Analysis and Systematic Review
por: Chen, Chang-Hung, et al.
Publicado: (2022)

NAXE gene mutation-related progressive encephalopathy: A case report and literature review
por: Chiu, Li-Wei, et al.
Publicado: (2021)

Comparative Incorporation of PNA into DNA Nanostructures
por: Pedersen, Ronnie O., et al.
Publicado: (2015)

Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma
por: Lin, Chun-Yu, et al.
Publicado: (2017)

PNA Length Restriction of Antibacterial Activity of Peptide-PNA Conjugates in Escherichia coli Through Effects of the Inner Membrane
por: Goltermann, Lise, et al.
Publicado: (2019)

Durable Response to Combined Dabrafenib and Trametinib in a Patient With BRAF K601E Mutation-Positive Lung Adenocarcinoma: A Case Report
por: Su, Po-Lan, et al.
Publicado: (2021)

Enhancing diagnosis of T-cell lymphoma using non-recombined T-cell receptor sequences
por: Chen, Yi-Lin, et al.
Publicado: (2022)

Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA
por: Liang, Yufeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4fpkir6maogu8raq9jeiu2tln0