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Deletion of Salmonella enterica serovar Typhi tolC reduces bacterial adhesion and invasion toward host cells

BACKGROUND: S. Typhi is a Gram-negative bacterium that causes typhoid fever in humans. Its virulence depends on the TolC outer membrane pump, which expels toxic compounds and antibiotics. However, the role of TolC in the host cell adhesion and invasion by S. Typhi is unclear. OBJECTIVE: We aimed to...

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Detalles Bibliográficos
Autores principales: Hussain, Ashraf, Ong, Eugene Boon Beng, Balaram, Prabha, Ismail, Asma, Kien, Phua Kia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655110/
https://www.ncbi.nlm.nih.gov/pubmed/38029101
http://dx.doi.org/10.3389/fmicb.2023.1301478