Cargando…

Operationalizing selection criteria for clinical trials in Alzheimer's disease: Biomarker and clinical considerations

Alzheimer's disease (AD) staging criteria lack standardized, empirical description. Well‐defined AD staging criteria are an important consideration in protocol design, influencing a more standardized inclusion/exclusion criteria and defining what constitutes meaningful differentiation among the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petersen, Ronald C., Graf, Ana, Brady, Chris, De Santi, Susan, Florian, Hana, Landen, Jaren, Pontecorvo, Mike, Randolph, Christopher, Sink, Kaycee M., Carrillo, Maria C., Weber, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655199/ https://www.ncbi.nlm.nih.gov/pubmed/38023620 http://dx.doi.org/10.1002/trc2.12434

Ejemplares similares

Operationalizing Stakeholder Engagement Through the Stakeholder-Centric Engagement Charter (SCEC)
por: Martínez, Jenny, et al.
Publicado: (2022)

Socially active neighborhoods: construct operationalization for aging in place, health promotion and psychometric testing
por: Asiamah, Nestor, et al.
Publicado: (2023)

Addressing path dependencies in decision-making processes for operationalizing compound climate-risk management
por: Thaler, Thomas, et al.
Publicado: (2023)

Building clinically relevant outcomes across the Alzheimer's disease spectrum
por: Rentz, Dorene M., et al.
Publicado: (2021)

Operationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce
por: Carrol, Enitan D., et al.
Publicado: (2023)

Operationalization of diagnostic criteria of DSM-5 somatic symptom disorders
por: Xiong, Nana, et al.
Publicado: (2017)

Site readiness practices for clinical trials – considerations for CTSA hubs
por: Viera, Laura, et al.
Publicado: (2023)

Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development
por: Rabinovici, Gil D., et al.
Publicado: (2016)

Clinical considerations of lipid target and goal in dyslipidemia control
por: Wu, Na-Qiong, et al.
Publicado: (2016)

Retinal Dystrophies and the Road to Treatment: Clinical Requirements and Considerations
por: Talib, Mays, et al.
Publicado: (2020)

The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations
por: Vaughn, Samuel E., et al.
Publicado: (2021)

Operationalizing Healthspan as an Outcome for Clinical Trials in Geroscience
por: Justice, Jamie
Publicado: (2021)

Current understanding of AD pathophysiology and impact of amyloid‐beta targeted treatments on biomarkers and clinical endpoints
por: Petersen, Ronald C., et al.
Publicado: (2022)

Decision making in clinical trials: Interim analyses, innovative design, and biomarkers
por: Welsh‐Bohmer, Kathleen A., et al.
Publicado: (2023)

The pathway to secondary prevention of Alzheimer's disease
por: McDade, Eric, et al.
Publicado: (2020)

Transition from physical to virtual visit format for a longitudinal brain aging study, in response to the Covid‐19 pandemic. Operationalizing adaptive methods and challenges
por: Udeh‐Momoh, Chinedu Theresa, et al.
Publicado: (2020)

Development of a Multidisciplinary Clinic for Patients with Ehlers Danlos Syndromes: Considerations and Strategies
por: Black, William R, et al.
Publicado: (2023)

Operationalizing undifferentiated affect: Validity and utility in clinical samples
por: Lane, Sean P., et al.
Publicado: (2022)

Operationalizing Sustainability
por: Massotte, Pierre
Publicado: (2015)

Operationalizing AI
por: Thomas, John, et al.
Publicado: (2021)

Perspective: Laboratory Considerations and Clinical Data Management for Human Nutrition Randomized Controlled Trials: Guidance for Ensuring Quality and Integrity
por: Maki, Kevin C, et al.
Publicado: (2020)

Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update
por: Banholzer, Maria Longauer, et al.
Publicado: (2016)

Operationalization of the physical frailty & sarcopenia syndrome: rationale and clinical implementation
por: Marzetti, E., et al.
Publicado: (2016)

Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies
por: Li, Yimei, et al.
Publicado: (2022)

A trans-diagnostic review of anxiety disorder comorbidity and the impact of multiple exclusion criteria on studying clinical outcomes in anxiety disorders
por: Goldstein-Piekarski, A N, et al.
Publicado: (2016)

Standardising Outcomes in Paediatric Clinical Trials
por: Clarke, Mike
Publicado: (2008)

Consideration of compound drivers and impacts in the disaster risk reduction cycle
por: van den Hurk, Bart J.J.M., et al.
Publicado: (2023)

Breakthrough Therapy Designation Criteria Identify Drugs that Improve Clinical Outcomes for Patients: A Case for More Streamlined Coverage of Promising Therapies
por: Collins, Grace, et al.
Publicado: (2023)

Occupational safety and health criteria for responsible development of nanotechnology
por: Schulte, P. A., et al.
Publicado: (2013)

Practical and Ethical Considerations in Telehealth: Pitfalls and Opportunities
por: Hull, Sarah C., et al.
Publicado: (2022)

Operationalization of the Clinical Frailty Scale in Korean Community-Dwelling Older People
por: Jung, Hee-Won, et al.
Publicado: (2022)

Perspective: Plant-Based Eating Pattern for Type 2 Diabetes Prevention and Treatment: Efficacy, Mechanisms, and Practical Considerations
por: Jardine, Meghan A, et al.
Publicado: (2021)

The importance of appropriate selection of clinical endpoints in outpatient COVID-19 clinical trials
por: Thorlund, Kristian, et al.
Publicado: (2023)

Organ-specific considerations for marginal zone lymphomas in Korea, based on Consortium for Improving Survival of Lymphoma (CISL) and Korean clinical studies
por: Oh, Sung Yong, et al.
Publicado: (2019)

Cognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's
por: Buettner, Linda L., et al.
Publicado: (2011)

Measuring cognition and function in the preclinical stage of Alzheimer's disease
por: Weintraub, Sandra, et al.
Publicado: (2018)

Neonatal Circumcision for HIV Prevention: Cost, Culture, and Behavioral Considerations
por: Kalichman, Seth C.
Publicado: (2010)

Operationalizing Surveillance of Chronic Disease Self-Management and Self-Management Support
por: Brady, Teresa J., et al.
Publicado: (2018)

Emerging treatments for lupus nephritis: health equity considerations in clinical research and coverage
por: Newman, Terri V, et al.
Publicado: (2021)

Myalgic Encephalomyelitis or What? The International Consensus Criteria
por: Twisk, Frank
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k9vj7b75cije68ctdu8au9qleu