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Effects of Doxorubicin on Extracellular Matrix Regulation in Primary Cardiac Fibroblasts from Mice

OBJECTIVE: Doxorubicin (DOX) is a highly effective chemotherapeutic used to treat many adult and pediatric cancers. However, its use is limited due to a dose-dependent cardiotoxicity, which can lead to lethal cardiomyopathy. In contrast to the extensive research efforts on toxic effects of DOX in ca...

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Detalles Bibliográficos
Autores principales:	Skaggs, Cameron, Nick, Steve, Patricelli, Conner, Bond, Laura, Woods, Kali, Woodbury, Luke, Oxford, Julia Thom, Pu, Xinzhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655342/ https://www.ncbi.nlm.nih.gov/pubmed/37974221 http://dx.doi.org/10.1186/s13104-023-06621-7

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