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Understanding the Genetics of Early-Onset Obesity in a Cohort of Children From Qatar

CONTEXT: Monogenic obesity is a rare form of obesity due to pathogenic variants in genes implicated in the leptin–melanocortin signaling pathway and accounts for around 5% of severe early-onset obesity. Mutations in the genes encoding the MC4R, leptin, and leptin receptor are commonly reported in va...

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Detalles Bibliográficos
Autores principales: Mohammed, Idris, Haris, Basma, Al-Barazenji, Tara, Vasudeva, Dhanya, Tomei, Sara, Al Azwani, Iman, Dauleh, Hajar, Shehzad, Saira, Chirayath, Shiga, Mohamadsalih, Ghassan, Petrovski, Goran, Khalifa, Amel, Love, Donald R, Al-Shafai, Mashael, Hussain, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655519/
https://www.ncbi.nlm.nih.gov/pubmed/37329217
http://dx.doi.org/10.1210/clinem/dgad366