(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol

(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps was 28%. The compound was identified and character...

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Detalles Bibliográficos
Autores principales: Gaynor, Ryan B., McIntyre, Baylee N., Creutz, Sidney E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655578/
https://www.ncbi.nlm.nih.gov/pubmed/37982079
http://dx.doi.org/10.3390/M1566
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author Gaynor, Ryan B.
McIntyre, Baylee N.
Creutz, Sidney E.
author_facet Gaynor, Ryan B.
McIntyre, Baylee N.
Creutz, Sidney E.
author_sort Gaynor, Ryan B.
collection PubMed
description (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps was 28%. The compound was identified and characterized by (1)H and (13)C{(1)H} NMR, high-resolution mass spectroscopy, and elemental analysis. This compound and its derivatives have the potential to be used as precursors to the synthesis of biomimetic chelating ligands.
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spelling pubmed-106555782023-11-17 (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol Gaynor, Ryan B. McIntyre, Baylee N. Creutz, Sidney E. Molbank Article (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps was 28%. The compound was identified and characterized by (1)H and (13)C{(1)H} NMR, high-resolution mass spectroscopy, and elemental analysis. This compound and its derivatives have the potential to be used as precursors to the synthesis of biomimetic chelating ligands. 2023-03 2023-01-23 /pmc/articles/PMC10655578/ /pubmed/37982079 http://dx.doi.org/10.3390/M1566 Text en https://creativecommons.org/licenses/by/4.0/This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gaynor, Ryan B.
McIntyre, Baylee N.
Creutz, Sidney E.
(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title_full (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title_fullStr (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title_full_unstemmed (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title_short (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
title_sort (4-(adamantan-1-yl)-1-(isopropyl)-1h-imidazol-2-yl)methanol
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655578/
https://www.ncbi.nlm.nih.gov/pubmed/37982079
http://dx.doi.org/10.3390/M1566
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