Synthesis, biological evaluation and in silico investigations of benzotriazole derivatives as potential inhibitors of NIMA related kinase

In the current study, a novel compound, bis(3-(2H-benzo[d][1,2,3]triazol-2-yl)-2-(prop-2-yn-1-yloxy)-5-(2,4,4-trimethylpentan-2-yl)phenyl)methane (TAJ1), has been synthesized by the reaction of 6,6′-methylenebis(2-(2H-benzo[d][1,2,3]triazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol) (1), propargyl...

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Detalles Bibliográficos
Autores principales: Qadri, Tahir, Aziz, Mubashir, Channar, Pervaiz Ali, Ejaz, Syeda Abida, Hussain, Mumtaz, Attaullah, Hafiz Muhammad, Ujan, Rabail, Hussain, Zahid, Zehra, Tasneem, Saeed, Aamer, Shah, M. R., Ogaly, Hanan A., Al-Zahrani, Fatimah A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655664/
https://www.ncbi.nlm.nih.gov/pubmed/38020022
http://dx.doi.org/10.1039/d3ra06149c

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