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Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit

The asymptomatic population's role in COVID-19 transmission poses challenges for control efforts. Pregnant women are susceptible to severe manifestations, increasing maternal and perinatal morbidity and mortality. This study describes the clinical characteristics, maternal and fetal outcomes, a...

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Autores principales: Escobar Vidarte, María Fernanda, Echavarria, Maria Paula, Carvajal, Javier Andrés, Albornoz, Ludwig Luis, Peña-Zarate, Evelyn E., Libreros, Laura, Nasner, Daniela, Vélez, Juan Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655671/
https://www.ncbi.nlm.nih.gov/pubmed/38026062
http://dx.doi.org/10.1177/23743735231213764
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author Escobar Vidarte, María Fernanda
Echavarria, Maria Paula
Carvajal, Javier Andrés
Albornoz, Ludwig Luis
Peña-Zarate, Evelyn E.
Libreros, Laura
Nasner, Daniela
Vélez, Juan Diego
author_facet Escobar Vidarte, María Fernanda
Echavarria, Maria Paula
Carvajal, Javier Andrés
Albornoz, Ludwig Luis
Peña-Zarate, Evelyn E.
Libreros, Laura
Nasner, Daniela
Vélez, Juan Diego
author_sort Escobar Vidarte, María Fernanda
collection PubMed
description The asymptomatic population's role in COVID-19 transmission poses challenges for control efforts. Pregnant women are susceptible to severe manifestations, increasing maternal and perinatal morbidity and mortality. This study describes the clinical characteristics, maternal and fetal outcomes, and our experience in universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening of pregnant women admitted to a high-complexity obstetric unit in Latin America. Of 568 pregnant women tested for SARS-CoV-2, 23 obtained a positive result. Among these patients, 17% had symptoms at admission, and 0.2% reported an epidemiological link. Pregnant women with positive were associated with an increased risk of eclampsia (16.7% vs 4.9%, P = .014) and acute respiratory distress (16.7% vs 4.9%, P = .014). In this group, 4 patients developed maternal near misses, and no maternal deaths were noted. Two early perinatal deaths occurred in the positive SARS-CoV-2 test group (2, 9.5% vs 17, 4.1%, P = .235). The high prevalence of asymptomatic pregnant women with SARS-CoV-2 and the adverse outcomes for those infected during pregnancy highlights the importance of universal screening upon hospital admission. This approach streamlines risk management, and enhances service structure, resource allocation, care pathways, patient management, follow-up, and overall outcomes.
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spelling pubmed-106556712023-11-15 Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit Escobar Vidarte, María Fernanda Echavarria, Maria Paula Carvajal, Javier Andrés Albornoz, Ludwig Luis Peña-Zarate, Evelyn E. Libreros, Laura Nasner, Daniela Vélez, Juan Diego J Patient Exp COVID-19: Patient and Clinician Experiences The asymptomatic population's role in COVID-19 transmission poses challenges for control efforts. Pregnant women are susceptible to severe manifestations, increasing maternal and perinatal morbidity and mortality. This study describes the clinical characteristics, maternal and fetal outcomes, and our experience in universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening of pregnant women admitted to a high-complexity obstetric unit in Latin America. Of 568 pregnant women tested for SARS-CoV-2, 23 obtained a positive result. Among these patients, 17% had symptoms at admission, and 0.2% reported an epidemiological link. Pregnant women with positive were associated with an increased risk of eclampsia (16.7% vs 4.9%, P = .014) and acute respiratory distress (16.7% vs 4.9%, P = .014). In this group, 4 patients developed maternal near misses, and no maternal deaths were noted. Two early perinatal deaths occurred in the positive SARS-CoV-2 test group (2, 9.5% vs 17, 4.1%, P = .235). The high prevalence of asymptomatic pregnant women with SARS-CoV-2 and the adverse outcomes for those infected during pregnancy highlights the importance of universal screening upon hospital admission. This approach streamlines risk management, and enhances service structure, resource allocation, care pathways, patient management, follow-up, and overall outcomes. SAGE Publications 2023-11-15 /pmc/articles/PMC10655671/ /pubmed/38026062 http://dx.doi.org/10.1177/23743735231213764 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle COVID-19: Patient and Clinician Experiences
Escobar Vidarte, María Fernanda
Echavarria, Maria Paula
Carvajal, Javier Andrés
Albornoz, Ludwig Luis
Peña-Zarate, Evelyn E.
Libreros, Laura
Nasner, Daniela
Vélez, Juan Diego
Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title_full Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title_fullStr Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title_full_unstemmed Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title_short Universal Screening for SARS-CoV-2 in Obstetric Care: Clinical Characteristics and Maternofetal Outcomes in a Latin American High-Complexity Unit
title_sort universal screening for sars-cov-2 in obstetric care: clinical characteristics and maternofetal outcomes in a latin american high-complexity unit
topic COVID-19: Patient and Clinician Experiences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655671/
https://www.ncbi.nlm.nih.gov/pubmed/38026062
http://dx.doi.org/10.1177/23743735231213764
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