A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management

Diffuse alveolar hemorrhage is a rare complication of antiphospholipid syndrome with high mortality rates. Early diagnosis and treatment with steroids and immunosuppressive agents, along with the achievement of hemostasis and hemodynamic stability, is critical to improving outcomes. This case demons...

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Detalles Bibliográficos
Autores principales: Ruzdija, Denis, Bertolo, Aaron, Pandya, Shaunak K, Amaraneni, Akshay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655834/
https://www.ncbi.nlm.nih.gov/pubmed/38022217
http://dx.doi.org/10.7759/cureus.47267
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author Ruzdija, Denis
Bertolo, Aaron
Pandya, Shaunak K
Amaraneni, Akshay
author_facet Ruzdija, Denis
Bertolo, Aaron
Pandya, Shaunak K
Amaraneni, Akshay
author_sort Ruzdija, Denis
collection PubMed
description Diffuse alveolar hemorrhage is a rare complication of antiphospholipid syndrome with high mortality rates. Early diagnosis and treatment with steroids and immunosuppressive agents, along with the achievement of hemostasis and hemodynamic stability, is critical to improving outcomes. This case demonstrates the complexity of managing refractory diffuse alveolar hemorrhage in a 48-year-old woman with antiphospholipid syndrome requiring treatment with high-dose corticosteroids, rituximab, and cyclophosphamide.
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spelling pubmed-106558342023-10-18 A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management Ruzdija, Denis Bertolo, Aaron Pandya, Shaunak K Amaraneni, Akshay Cureus Internal Medicine Diffuse alveolar hemorrhage is a rare complication of antiphospholipid syndrome with high mortality rates. Early diagnosis and treatment with steroids and immunosuppressive agents, along with the achievement of hemostasis and hemodynamic stability, is critical to improving outcomes. This case demonstrates the complexity of managing refractory diffuse alveolar hemorrhage in a 48-year-old woman with antiphospholipid syndrome requiring treatment with high-dose corticosteroids, rituximab, and cyclophosphamide. Cureus 2023-10-18 /pmc/articles/PMC10655834/ /pubmed/38022217 http://dx.doi.org/10.7759/cureus.47267 Text en Copyright © 2023, Ruzdija et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Ruzdija, Denis
Bertolo, Aaron
Pandya, Shaunak K
Amaraneni, Akshay
A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title_full A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title_fullStr A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title_full_unstemmed A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title_short A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management
title_sort case report of refractory diffuse alveolar hemorrhage as a complication of antiphospholipid syndrome and review of its management
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655834/
https://www.ncbi.nlm.nih.gov/pubmed/38022217
http://dx.doi.org/10.7759/cureus.47267
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