Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation

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Recent studies have identified increasing levels of nanoplastic pollution in the environment. Here, we find that anionic nanoplastic contaminants potently precipitate the formation and propagation of α-synuclein protein fibrils through a high-affinity interaction with the amphipathic and non-amyloid...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyong, Sokratian, Arpine, Duda, Addison M., Xu, Enquan, Stanhope, Christina, Fu, Amber, Strader, Samuel, Li, Huizhong, Yuan, Yuan, Bobay, Benjamin G., Sipe, Joana, Bai, Ketty, Lundgaard, Iben, Liu, Na, Hernandez, Belinda, Bowes Rickman, Catherine, Miller, Sara E., West, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656074/
https://www.ncbi.nlm.nih.gov/pubmed/37976362
http://dx.doi.org/10.1126/sciadv.adi8716

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