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The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks

Tumors anomalously induce the expression of meiotic genes, which are otherwise restricted only to developing gametes. If and how these aberrantly expressed meiotic proteins influence DNA metabolism is not clear, but could have important implications for how tumors acquire and mitigate genomic instab...

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Detalles Bibliográficos
Autores principales:	Herrera, Luis Reza, Johnson, Ronnesha A., McGlynn, Kathleen, Gibbs, Zane A., Davis, Anthony J., Whitehurst, Angelique W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656231/ https://www.ncbi.nlm.nih.gov/pubmed/37838177 http://dx.doi.org/10.1016/j.jbc.2023.105348

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