Enzyme-less nanopore detection of post-translational modifications within long polypeptides

Means to analyse cellular proteins and their millions of variants at the single-molecule level would uncover substantial information previously unknown to biology. Nanopore technology, which underpins long-read DNA and RNA sequencing, holds potential for full-length proteoform identification. We use...

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Detalles Bibliográficos
Autores principales: Martin-Baniandres, Pablo, Lan, Wei-Hsuan, Board, Stephanie, Romero-Ruiz, Mercedes, Garcia-Manyes, Sergi, Qing, Yujia, Bayley, Hagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656283/
https://www.ncbi.nlm.nih.gov/pubmed/37500774
http://dx.doi.org/10.1038/s41565-023-01462-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656283/
https://www.ncbi.nlm.nih.gov/pubmed/37500774
http://dx.doi.org/10.1038/s41565-023-01462-8

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