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Enzyme-less nanopore detection of post-translational modifications within long polypeptides
Means to analyse cellular proteins and their millions of variants at the single-molecule level would uncover substantial information previously unknown to biology. Nanopore technology, which underpins long-read DNA and RNA sequencing, holds potential for full-length proteoform identification. We use...
Autores principales: | Martin-Baniandres, Pablo, Lan, Wei-Hsuan, Board, Stephanie, Romero-Ruiz, Mercedes, Garcia-Manyes, Sergi, Qing, Yujia, Bayley, Hagan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656283/ https://www.ncbi.nlm.nih.gov/pubmed/37500774 http://dx.doi.org/10.1038/s41565-023-01462-8 |
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