S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate receptor 1 (S1PR1) has been implicated in various cancer types, including ovarian cancer. The...

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Detalles Bibliográficos
Autores principales: Tao, Yi-Ping, Zhu, Heng-Yan, Shi, Qian-Yuan, Wang, Cai-Xia, Hua, Yu-Xin, Hu, Han-Yin, Zhou, Qi-Yin, Zhou, Zi-Lu, Sun, Ying, Wang, Xiao-Min, Wang, Yu, Zhang, Ya-Ling, Guo, Yan-Jun, Wang, Zi-Ying, Che, Xuan, Xu, Chun-Wei, Zhang, Xian-Chao, Heger, Michal, Tao, Su-Ping, Zheng, Xin, Xu, Ying, Ao, Lei, Liu, Ai-Jun, Liu, Sheng-Bing, Cheng, Shu-Qun, Pan, Wei-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656284/
https://www.ncbi.nlm.nih.gov/pubmed/37828220
http://dx.doi.org/10.1038/s41388-023-02853-w

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