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Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment

In the rapidly advancing field of synthetic biology, there exists a critical need for technology to discover targeting moieties for therapeutic biologics. Here we present INSPIRE-seq, an approach that utilizes a nanobody library and next-generation sequencing to identify nanobodies selected for comp...

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Detalles Bibliográficos
Autores principales:	Sekar, Thillai V., Elghonaimy, Eslam A., Swancutt, Katy L., Diegeler, Sebastian, Gonzalez, Isaac, Hamilton, Cassandra, Leung, Peter Q., Meiler, Jens, Martina, Cristina E., Whitney, Michael, Aguilera, Todd A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656474/ https://www.ncbi.nlm.nih.gov/pubmed/37978291 http://dx.doi.org/10.1038/s41467-023-43038-z

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