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SEPTIN2 suppresses an IFN-γ-independent, proinflammatory macrophage activation pathway

Interferon-gamma (IFN-γ) signaling is necessary for the proinflammatory activation of macrophages but IFN-γ-independent pathways, for which the initiating stimuli and downstream mechanisms are lesser known, also contribute. Here we identify, by high-content screening, SEPTIN2 (SEPT2) as a negative r...

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Detalles Bibliográficos
Autores principales:	Fu, Beibei, Xiong, Yan, Sha, Zhou, Xue, Weiwei, Xu, Binbin, Tan, Shun, Guo, Dong, Lin, Feng, Wang, Lulu, Ji, Jianjian, Luo, Yang, Lin, Xiaoyuan, Wu, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656488/ https://www.ncbi.nlm.nih.gov/pubmed/37978190 http://dx.doi.org/10.1038/s41467-023-43283-2

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