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Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets

Darier disease (DD) is a rare, inherited multi-organ disorder associated with mutations in the ATP2A2 gene. DD patients often have skin involvement characterized by malodorous, inflamed skin and recurrent, severe infections. Therapeutic options are limited and inadequate for the long-term management...

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Detalles Bibliográficos
Autores principales: Ettinger, Monika, Burner, Teresa, Sharma, Anshu, Chang, Yun-Tsan, Lackner, Angelika, Prompsy, Pacôme, Deli, Isabella M., Traxler, Judith, Wahl, Gerald, Altrichter, Sabine, Langer, Rupert, Tsai, Yi-Chien, Varkhande, Suraj R., Schoeftner, Leonie C., Iselin, Christoph, Gratz, Iris K., Kimeswenger, Susanne, Guenova, Emmanuella, Hoetzenecker, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656568/
https://www.ncbi.nlm.nih.gov/pubmed/37978298
http://dx.doi.org/10.1038/s41467-023-43210-5