Case report: Deep molecular remissions post two separate CD19-targeted chimeric antigen receptor T-cell therapies do not prevent disease from relapsing in Philadelphia chromosome-positive acute lymphoblastic leukemia

Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) is an aggressive B-cell malignancy. The management of a relapsed Ph+ ALL patient is challenging. Currently, either allogeneic stem cell transplant (allo-SCT) or CD19-targeted chimeric antigen receptor T-cell (CAR T-cell) are usu...

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Detalles Bibliográficos
Autores principales: Tang, Yu, Fei, Xiaoming, Yu, Xianqiu, Cao, Jiang, Wang, Lixia, Lei, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656679/
https://www.ncbi.nlm.nih.gov/pubmed/38023231
http://dx.doi.org/10.3389/fonc.2023.1251738

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