Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the start of the pandemic, olfactory dysfunction (OD) has been reported as a common symptom of COVID-19. In some asymptomatic carriers, OD is often the first...

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Autores principales: Hu, Bian, Gong, Mengdan, Xiang, Yizhen, Qu, Siyuan, Zhu, Hai, Ye, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657033/
https://www.ncbi.nlm.nih.gov/pubmed/37978386
http://dx.doi.org/10.1186/s12967-023-04719-x
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author Hu, Bian
Gong, Mengdan
Xiang, Yizhen
Qu, Siyuan
Zhu, Hai
Ye, Dong
author_facet Hu, Bian
Gong, Mengdan
Xiang, Yizhen
Qu, Siyuan
Zhu, Hai
Ye, Dong
author_sort Hu, Bian
collection PubMed
description Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the start of the pandemic, olfactory dysfunction (OD) has been reported as a common symptom of COVID-19. In some asymptomatic carriers, OD is often the first and even the only symptom. At the same time, persistent OD is also a long-term sequela seen after COVID-19 that can have a serious impact on the quality of life of patients. However, the pathogenesis of post-COVID-19 OD is still unclear, and there is no specific treatment for its patients. The aim of this paper was to review the research on OD caused by SARS-CoV-2 infection and to summarize the mechanism of action, the pathogenesis, and current treatments.
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spelling pubmed-106570332023-11-17 Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019 Hu, Bian Gong, Mengdan Xiang, Yizhen Qu, Siyuan Zhu, Hai Ye, Dong J Transl Med Review Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the start of the pandemic, olfactory dysfunction (OD) has been reported as a common symptom of COVID-19. In some asymptomatic carriers, OD is often the first and even the only symptom. At the same time, persistent OD is also a long-term sequela seen after COVID-19 that can have a serious impact on the quality of life of patients. However, the pathogenesis of post-COVID-19 OD is still unclear, and there is no specific treatment for its patients. The aim of this paper was to review the research on OD caused by SARS-CoV-2 infection and to summarize the mechanism of action, the pathogenesis, and current treatments. BioMed Central 2023-11-17 /pmc/articles/PMC10657033/ /pubmed/37978386 http://dx.doi.org/10.1186/s12967-023-04719-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Hu, Bian
Gong, Mengdan
Xiang, Yizhen
Qu, Siyuan
Zhu, Hai
Ye, Dong
Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title_full Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title_fullStr Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title_full_unstemmed Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title_short Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
title_sort mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657033/
https://www.ncbi.nlm.nih.gov/pubmed/37978386
http://dx.doi.org/10.1186/s12967-023-04719-x
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