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Inferring mitochondrial and cytosolic metabolism by coupling isotope tracing and deconvolution

The inability to inspect metabolic activities within distinct subcellular compartments has been a major barrier to our understanding of eukaryotic cell metabolism. Previous work addressed this challenge by analyzing metabolism in isolated organelles, which grossly bias metabolic activity. Here, we d...

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Detalles Bibliográficos
Autores principales: Stern, Alon, Fokra, Mariam, Sarvin, Boris, Alrahem, Ahmad Abed, Lee, Won Dong, Aizenshtein, Elina, Sarvin, Nikita, Shlomi, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657349/
https://www.ncbi.nlm.nih.gov/pubmed/37980339
http://dx.doi.org/10.1038/s41467-023-42824-z