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Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression

Receptor for activated C kinase 1 (RACK1) has been confirmed to take part in multiple biological events and the mechanism supporting abnormal RACK1 expression in ovarian cancer (OC) remains to be characterized. Here, we identified Smad ubiquitin regulatory factor 2 (SMURF2) as a bona fide E3 ligase...

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Detalles Bibliográficos
Autores principales: Pi, Yanan, Feng, Qiushi, Sun, Fusheng, Wang, Zhiqiang, Zhao, Yue, Chen, Dejia, Liu, Yiming, Lou, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657365/
https://www.ncbi.nlm.nih.gov/pubmed/37828084
http://dx.doi.org/10.1038/s41418-023-01226-w

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