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Inhibition of PDGFRβ alleviates endothelial cell apoptotic injury caused by DRP-1 overexpression and mitochondria fusion failure after mitophagy

ABSTRACT: Kawasaki disease (KD), described as “mucocutaneous lymph node syndrome”, affects infants and toddlers. Patients with KD suffer from an inflammatory cascade leading to vasculitis with a predilection for coronary arteries. While the symptoms and pathogenesis of KD have received more and more...

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Detalles Bibliográficos
Autores principales: An, Xiaohong, Ma, Xiao, Liu, Heng, Song, Jing, Wei, Tiange, Zhang, Rongzhan, Zhan, Xiao, Li, Hongyang, Zhou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657461/
https://www.ncbi.nlm.nih.gov/pubmed/37980402
http://dx.doi.org/10.1038/s41419-023-06272-3