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PAC1 deficiency reduces chondrogenesis in atherosclerotic lesions of hypercholesterolemic ApoE-deficient mice

BACKGROUND: Induction of chondrogenesis is associated with progressive atherosclerosis. Deficiency of the ADCYAP1 gene encoding pituitary adenylate cyclase-activating peptide (PACAP) aggravates atherosclerosis in ApoE deficient (ApoE(−/−)) mice. PACAP signaling regulates chondrogenesis and osteogene...

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Detalles Bibliográficos
Autores principales: Blümm, C., Bonaterra, G. A., Schwarzbach, H., Eiden, L. E., Weihe, E., Kinscherf, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657554/
https://www.ncbi.nlm.nih.gov/pubmed/37980508
http://dx.doi.org/10.1186/s12872-023-03600-5

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