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Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progression

BACKGROUND: Glycolytic metabolic reprogramming is a phenomenon in which cells undergo altered metabolic patterns during malignant transformation, mainly involving various aspects of glycolysis, electron transport chain, oxidative phosphorylation, and pentose phosphate pathway. This reprogramming phe...

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Detalles Bibliográficos
Autores principales: Zhao, Hongying, Jiang, Rongke, Feng, Zhijing, Wang, Xue, Zhang, Chunmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657563/
https://www.ncbi.nlm.nih.gov/pubmed/37980488
http://dx.doi.org/10.1186/s12967-023-04658-7

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