The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia

PURPOSE: Several studies have explored the relationship between level of education and medication adherence, as well as the relationship between level of education and cognitive function. However, there have been few studies on the relationships between level of education, cognitive function, and me...

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Autores principales: Zhu, Xiaodan, Wen, Min, He, Ying, Feng, Jing, Xu, Xuebing, Liu, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657742/
https://www.ncbi.nlm.nih.gov/pubmed/38029047
http://dx.doi.org/10.2147/NDT.S424694
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author Zhu, Xiaodan
Wen, Min
He, Ying
Feng, Jing
Xu, Xuebing
Liu, Juan
author_facet Zhu, Xiaodan
Wen, Min
He, Ying
Feng, Jing
Xu, Xuebing
Liu, Juan
author_sort Zhu, Xiaodan
collection PubMed
description PURPOSE: Several studies have explored the relationship between level of education and medication adherence, as well as the relationship between level of education and cognitive function. However, there have been few studies on the relationships between level of education, cognitive function, and medication adherence. This study aimed to explore whether cognitive function has a mediating effect between level of education and medication adherence in patients with schizophrenia. PATIENTS AND METHODS: A total of 329 participants were included in this study. Cognitive function was assessed using the Brief Assessment of Cognition in Schizophrenia, and medication adherence using the Medication Adherence Questionnaire. The relationships between the clinical factors and cognitive function that contributed to medication adherence were tested through multivariable linear regression analysis. The mediating effect of medication adherence was tested using the bootstrapping approach with the PROCESS macro. RESULTS: Family history, insight and executive function were associated with medication adherence in individuals with schizophrenia, and executive function had a mediating effect between level of education and medication adherence. CONCLUSION: Adopting specific education programs that promote cognitive development as well as actively intervening in executive function might be conducive to improve medication adherence in patients with schizophrenia.
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spelling pubmed-106577422023-11-15 The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia Zhu, Xiaodan Wen, Min He, Ying Feng, Jing Xu, Xuebing Liu, Juan Neuropsychiatr Dis Treat Original Research PURPOSE: Several studies have explored the relationship between level of education and medication adherence, as well as the relationship between level of education and cognitive function. However, there have been few studies on the relationships between level of education, cognitive function, and medication adherence. This study aimed to explore whether cognitive function has a mediating effect between level of education and medication adherence in patients with schizophrenia. PATIENTS AND METHODS: A total of 329 participants were included in this study. Cognitive function was assessed using the Brief Assessment of Cognition in Schizophrenia, and medication adherence using the Medication Adherence Questionnaire. The relationships between the clinical factors and cognitive function that contributed to medication adherence were tested through multivariable linear regression analysis. The mediating effect of medication adherence was tested using the bootstrapping approach with the PROCESS macro. RESULTS: Family history, insight and executive function were associated with medication adherence in individuals with schizophrenia, and executive function had a mediating effect between level of education and medication adherence. CONCLUSION: Adopting specific education programs that promote cognitive development as well as actively intervening in executive function might be conducive to improve medication adherence in patients with schizophrenia. Dove 2023-11-15 /pmc/articles/PMC10657742/ /pubmed/38029047 http://dx.doi.org/10.2147/NDT.S424694 Text en © 2023 Zhu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Zhu, Xiaodan
Wen, Min
He, Ying
Feng, Jing
Xu, Xuebing
Liu, Juan
The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title_full The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title_fullStr The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title_full_unstemmed The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title_short The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia
title_sort relationship between level of education, cognitive function and medication adherence in patients with schizophrenia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657742/
https://www.ncbi.nlm.nih.gov/pubmed/38029047
http://dx.doi.org/10.2147/NDT.S424694
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