Deletion of TRPC6, an Autism Risk Gene, Induces Hyperexcitability in Cortical Neurons Derived from Human Pluripotent Stem Cells

Autism spectrum disorder (ASD) is a complex and heterogeneous neurodevelopmental disorder linked to numerous rare, inherited, and arising de novo genetic variants. ASD often co-occurs with attention-deficit hyperactivity disorder and epilepsy, which are associated with hyperexcitability of neurons....

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Detalles Bibliográficos
Autores principales: Shin, Kyung Chul, Ali, Gowher, Ali Moussa, Houda Yasmine, Gupta, Vijay, de la Fuente, Alberto, Kim, Hyung-Goo, Stanton, Lawrence W., Park, Yongsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657791/
https://www.ncbi.nlm.nih.gov/pubmed/37552395
http://dx.doi.org/10.1007/s12035-023-03527-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657791/
https://www.ncbi.nlm.nih.gov/pubmed/37552395
http://dx.doi.org/10.1007/s12035-023-03527-0

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