The transcription factor ELF4 alleviates inflammatory bowel disease by activating IL1RN transcription, suppressing inflammatory TH17 cell activity, and inducing macrophage M2 polarization

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder affecting millions worldwide. Due to the complexity of its pathogenesis, the treatment options for IBD are limited. This study focuses on ELF4, a member of the ETS transcription factor family, as a target to elucidate...

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Detalles Bibliográficos
Autores principales: Cao, Meiwan, Chen, Peiyu, Peng, Baoling, Cheng, Yang, Xie, Jing, Hou, Ziang, Chen, Huan, Ye, Liping, Li, Huiwen, Wang, Hongli, Ren, Lu, Xiong, Liya, Geng, Lanlan, Gong, Sitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657822/
https://www.ncbi.nlm.nih.gov/pubmed/38022496
http://dx.doi.org/10.3389/fimmu.2023.1270411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657822/
https://www.ncbi.nlm.nih.gov/pubmed/38022496
http://dx.doi.org/10.3389/fimmu.2023.1270411

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