Genetic Polymorphisms Involved in Bladder Cancer: A Global Review

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244...

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Detalles Bibliográficos
Autores principales: Kourie, Hampig Raphael, Zouein, Joseph, Succar, Bahaa, Mardirossian, Avedis, Ahmadieh, Nizar, Chouery, Eliane, Mehawej, Cybel, Jalkh, Nadine, kattan, Joseph, Nemr, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Health Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657888/
https://www.ncbi.nlm.nih.gov/pubmed/38025894
http://dx.doi.org/10.3389/or.2023.10603
Descripción
Sumario:Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244 genes. The selected 455 SNPs were further investigated. All SNPs that were associated with smoking and environmental exposure were excluded from this study. A total of 197 genes and 343 SNPs were found to be associated with BC, among which 177 genes and 291 SNPs had congruent results across all available studies. These genes and SNPs were classified into eight different categories according to their function.

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