Genetic Polymorphisms Involved in Bladder Cancer: A Global Review

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244...

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Autores principales: Kourie, Hampig Raphael, Zouein, Joseph, Succar, Bahaa, Mardirossian, Avedis, Ahmadieh, Nizar, Chouery, Eliane, Mehawej, Cybel, Jalkh, Nadine, kattan, Joseph, Nemr, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Health Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657888/
https://www.ncbi.nlm.nih.gov/pubmed/38025894
http://dx.doi.org/10.3389/or.2023.10603
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author Kourie, Hampig Raphael
Zouein, Joseph
Succar, Bahaa
Mardirossian, Avedis
Ahmadieh, Nizar
Chouery, Eliane
Mehawej, Cybel
Jalkh, Nadine
kattan, Joseph
Nemr, Elie
author_facet Kourie, Hampig Raphael
Zouein, Joseph
Succar, Bahaa
Mardirossian, Avedis
Ahmadieh, Nizar
Chouery, Eliane
Mehawej, Cybel
Jalkh, Nadine
kattan, Joseph
Nemr, Elie
author_sort Kourie, Hampig Raphael
collection PubMed
description Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244 genes. The selected 455 SNPs were further investigated. All SNPs that were associated with smoking and environmental exposure were excluded from this study. A total of 197 genes and 343 SNPs were found to be associated with BC, among which 177 genes and 291 SNPs had congruent results across all available studies. These genes and SNPs were classified into eight different categories according to their function.
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spelling pubmed-106578882023-11-06 Genetic Polymorphisms Involved in Bladder Cancer: A Global Review Kourie, Hampig Raphael Zouein, Joseph Succar, Bahaa Mardirossian, Avedis Ahmadieh, Nizar Chouery, Eliane Mehawej, Cybel Jalkh, Nadine kattan, Joseph Nemr, Elie Oncol Rev Health Archive Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244 genes. The selected 455 SNPs were further investigated. All SNPs that were associated with smoking and environmental exposure were excluded from this study. A total of 197 genes and 343 SNPs were found to be associated with BC, among which 177 genes and 291 SNPs had congruent results across all available studies. These genes and SNPs were classified into eight different categories according to their function. Frontiers Media S.A. 2023-11-06 /pmc/articles/PMC10657888/ /pubmed/38025894 http://dx.doi.org/10.3389/or.2023.10603 Text en Copyright © 2023 Kourie, Zouein, Succar, Mardirossian, Ahmadieh, Chouery, Mehawej, Jalkh, kattan and Nemr. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Health Archive
Kourie, Hampig Raphael
Zouein, Joseph
Succar, Bahaa
Mardirossian, Avedis
Ahmadieh, Nizar
Chouery, Eliane
Mehawej, Cybel
Jalkh, Nadine
kattan, Joseph
Nemr, Elie
Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title_full Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title_fullStr Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title_full_unstemmed Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title_short Genetic Polymorphisms Involved in Bladder Cancer: A Global Review
title_sort genetic polymorphisms involved in bladder cancer: a global review
topic Health Archive
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657888/
https://www.ncbi.nlm.nih.gov/pubmed/38025894
http://dx.doi.org/10.3389/or.2023.10603
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