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CYP450 and drug efflux transporters polymorphism influence clinical outcomes of Thai osimertinib-treated non-small cell lung cancer patients

Background: Osimertinib has shown greater efficacy than standard epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and fewer grade 3 or higher adverse drug reactions (ADRs) in patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (...

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Detalles Bibliográficos
Autores principales:	Majam, Teerapat, Sukasem, Chonlaphat, Reungwetwattana, Thanyanan, Chansriwong, Phichai, Atasilp, Chalirmporn, Trachu, Narumol, Thamrongjirapat, Thanaporn, Sukprasong, Rattanaporn, Meanwatthana, Jennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657898/ https://www.ncbi.nlm.nih.gov/pubmed/38026963 http://dx.doi.org/10.3389/fphar.2023.1222435

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