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Mechanisms of action of the BCL-2 inhibitor venetoclax in multiple myeloma: a literature review

Abnormal cellular apoptosis plays a pivotal role in the pathogenesis of Multiple Myeloma (MM). Over the years, BCL-2, a crucial anti-apoptotic protein, has garnered significant attention in MM therapeutic research. Venetoclax (VTC), a small-molecule targeted agent, effectively inhibits BCL-2, promot...

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Detalles Bibliográficos
Autores principales:	Cao, Qiang, Wu, Xinyan, Zhang, Qi, Gong, Junling, Chen, Yuquan, You, Yanwei, Shen, Jun, Qiang, Yi, Cao, Guangzhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657905/ https://www.ncbi.nlm.nih.gov/pubmed/38026941 http://dx.doi.org/10.3389/fphar.2023.1291920

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