IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver Disease

Many people living with diabetes also have nonalcoholic fatty liver disease (NAFLD). Interleukin-6 (IL-6) is involved in both diseases, interacting with both membrane-bound (classical) and circulating (trans-signaling) soluble receptors. We investigated whether secretion of IL-6 trans-signaling core...

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Detalles Bibliográficos
Autores principales: Gunes, Aysim, Schmitt, Clémence, Bilodeau, Laurent, Huet, Catherine, Belblidia, Assia, Baldwin, Cindy, Giard, Jeanne-Marie, Biertho, Laurent, Lafortune, Annie, Couture, Christian Yves, Cheung, Angela, Nguyen, Bich N., Galun, Eithan, Bémeur, Chantal, Bilodeau, Marc, Laplante, Mathieu, Tang, An, Faraj, May, Estall, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658070/
https://www.ncbi.nlm.nih.gov/pubmed/37757741
http://dx.doi.org/10.2337/db23-0171

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