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Humanized CD36 (hCD36) mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36

CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates lipid uptake, advanced oxidation protein products, and immunological recognition, and has roles in lipid accumulation, apoptosis, as well as in metastatic colonization in cancer. CD36 is involved in tumor immunity...

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Detalles Bibliográficos
Autores principales: Xie, Xiulong, Niu, Zhenlan, Wang, Linlin, Zhou, Xiaofei, Yu, Xingyan, Jing, Hongyan, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658083/
https://www.ncbi.nlm.nih.gov/pubmed/37407484
http://dx.doi.org/10.1538/expanim.23-0021