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New Biomarkers for Cardiovascular Disease
Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Texas Heart® Institute, Houston
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658139/ https://www.ncbi.nlm.nih.gov/pubmed/37846107 http://dx.doi.org/10.14503/THIJ-23-8178 |
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author | Kim, Stephanie J. Mesquita, Fernanda C. P. Hochman-Mendez, Camila |
author_facet | Kim, Stephanie J. Mesquita, Fernanda C. P. Hochman-Mendez, Camila |
author_sort | Kim, Stephanie J. |
collection | PubMed |
description | Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to increase worldwide as the global population ages. To address this problem, novel biomarkers that are more sensitive and specific to cardiovascular diseases must be developed and incorporated into clinical practice. Exosomes are promising biomarkers for cardiovascular disease. These small vesicles are produced and released into body fluids by all cells and carry specific information that can be correlated with disease progression. This article reviews the advantages and limitations of existing biomarkers for cardiovascular disease, such as cardiac troponin and cytokines, and discusses recent evidence suggesting the promise of exosomes as cardiovascular disease biomarkers. |
format | Online Article Text |
id | pubmed-10658139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Texas Heart® Institute, Houston |
record_format | MEDLINE/PubMed |
spelling | pubmed-106581392023-12-05 New Biomarkers for Cardiovascular Disease Kim, Stephanie J. Mesquita, Fernanda C. P. Hochman-Mendez, Camila Tex Heart Inst J Narrative Review Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to increase worldwide as the global population ages. To address this problem, novel biomarkers that are more sensitive and specific to cardiovascular diseases must be developed and incorporated into clinical practice. Exosomes are promising biomarkers for cardiovascular disease. These small vesicles are produced and released into body fluids by all cells and carry specific information that can be correlated with disease progression. This article reviews the advantages and limitations of existing biomarkers for cardiovascular disease, such as cardiac troponin and cytokines, and discusses recent evidence suggesting the promise of exosomes as cardiovascular disease biomarkers. Texas Heart® Institute, Houston 2023-10-17 /pmc/articles/PMC10658139/ /pubmed/37846107 http://dx.doi.org/10.14503/THIJ-23-8178 Text en © 2023 The Author(s). Published by The Texas Heart Institute® https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use and distribution in any medium, provided the original work is properly cited, and the use is noncommercial. |
spellingShingle | Narrative Review Kim, Stephanie J. Mesquita, Fernanda C. P. Hochman-Mendez, Camila New Biomarkers for Cardiovascular Disease |
title | New Biomarkers for Cardiovascular Disease |
title_full | New Biomarkers for Cardiovascular Disease |
title_fullStr | New Biomarkers for Cardiovascular Disease |
title_full_unstemmed | New Biomarkers for Cardiovascular Disease |
title_short | New Biomarkers for Cardiovascular Disease |
title_sort | new biomarkers for cardiovascular disease |
topic | Narrative Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658139/ https://www.ncbi.nlm.nih.gov/pubmed/37846107 http://dx.doi.org/10.14503/THIJ-23-8178 |
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