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Brain-to-gut trafficking of alpha-synuclein by CD11c(+) cells in a mouse model of Parkinson’s disease

Inflammation in the brain and gut is a critical component of several neurological diseases, such as Parkinson’s disease (PD). One trigger of the immune system in PD is aggregation of the pre-synaptic protein, α-synuclein (αSyn). Understanding the mechanism of propagation of αSyn aggregates is essent...

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Detalles Bibliográficos
Autores principales:	McFleder, Rhonda L., Makhotkina, Anastasiia, Groh, Janos, Keber, Ursula, Imdahl, Fabian, Peña Mosca, Josefina, Peteranderl, Alina, Wu, Jingjing, Tabuchi, Sawako, Hoffmann, Jan, Karl, Ann-Kathrin, Pagenstecher, Axel, Vogel, Jörg, Beilhack, Andreas, Koprich, James B., Brotchie, Jonathan M., Saliba, Antoine-Emmanuel, Volkmann, Jens, Ip, Chi Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658151/ https://www.ncbi.nlm.nih.gov/pubmed/37981650 http://dx.doi.org/10.1038/s41467-023-43224-z

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