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Canonical and non-canonical functions of NLRP3

BACKGROUND: Since its discovery, NLRP3 is almost never separated from its major role in the protein complex it forms with ASC, NEK7 and Caspase-1, the inflammasome. This key component of the innate immune response mediates the secretion of proinflammatory cytokines IL-1β and IL-18 involved in immune...

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Detalles Bibliográficos
Autores principales:	Accogli, Théo, Hibos, Christophe, Vegran, Frédérique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658328/ https://www.ncbi.nlm.nih.gov/pubmed/36610670 http://dx.doi.org/10.1016/j.jare.2023.01.001

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